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BPS BPS-Pharmacotherapy Exam Syllabus Topics:

SectionObjectives
Topic 1: Part I: Knowledge-Based Assessment- Foundational pharmacotherapy knowledge
  • 1. Drug mechanisms and clinical use
    • 2. Guideline-based treatment approaches
      Topic 2: Special Populations- Renal and hepatic impairment
      • 1. Dose adjustment strategies
        - Pediatrics and geriatrics
        • 1. Age-specific pharmacotherapy considerations
          Topic 3: Patient Care and Pharmacotherapy Principles- Medication management
          • 1. Dosing optimization and adjustments
            • 2. Adverse drug reaction management
              - Therapeutic decision making
              • 1. Evidence-based medicine application
                • 2. Drug selection and individualized therapy
                  Topic 4: Part II: Applied Clinical Decision Making- Case-based pharmacotherapy scenarios
                  • 1. Therapeutic optimization in multi-morbidity
                    • 2. Complex patient management cases
                      Topic 5: Disease State Management- Cardiovascular disorders
                      • 1. Hypertension and heart failure
                        • 2. Acute coronary syndromes
                          - Endocrine and metabolic disorders
                          • 1. Diabetes management
                            • 2. Thyroid and lipid disorders
                              - Infectious diseases
                              • 1. Antimicrobial therapy selection
                                • 2. Resistance management principles

                                  BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

                                  1. A 42-year-old woman is diagnosed with deep vein thrombosis. Heparin therapy is initiated with
                                  5,000 units as a single bolus injection, followed by an initial infusion rate of 1,000 units/h. The aPTT measured 6 hours later is >150 sec. Which of the following would be the most appropriate action at this time?

                                  A) Continue the infusion at 1,000 units/h, since the aPTT was drawn too early and is not useful.
                                  B) Stop the infusion for one hour, then resume at 750 units/h.
                                  C) Stop the infusion until the aPTT falls to <50 sec, and then resume at 750 units/h.
                                  D) Administer protamine 5 mg, and decrease the infusion rate to 750 units/h.


                                  2. A 67-year-old patient is hospitalized for decompensated heart failure. The serum sodium concentration is 130 mEq/L on admission. Which of the following is the most appropriate approach to managing the patient's hyponatremia?

                                  A) Restriction of both sodium and fluids
                                  B) 0.9% NaCl 200 mL/h intravenously for 5 hours
                                  C) 3% NaCl 50 mL/h intravenously for 5 hours
                                  D) Conivaptan 20 mg intravenously over 24 hours


                                  3. The risk of methemoglobinemia is highest with the use of:

                                  A) benzocaine 10% oral gel in a 67-year-old for oral pain associated with ill-fitting dentures.
                                  B) benzocaine 6% topical cream in a 25-year-old for pain associated with a sunburn.
                                  C) benzocaine 7.5% oral gel in an 18-month-old for oral pain associated with teething.
                                  D) benzocaine 20% topical cream in a 42-year-old for pain associated with insect bites.


                                  4. What is the most appropriate source for identifying the generic name, classification, and adverse effects of a foreign brand-name medication?

                                  A) American Hospital Formulary Service Drug information
                                  B) Micromedex
                                  C) Martindale: The Complete Drug Reference
                                  D) Drug Facts & Comparisons


                                  5. A 50-year-old woman experienced acute renal failure after receiving contrast dye for an imaging study. Her estimated creatinine clearance is now 20 mL/min. Her medications include:
                                  * Piperacillin/tazobactam 4.5g intravenously every 8 hours
                                  * Azithromycin 500 mg intravenously daily
                                  * Famotidine 40 mg orally twice daily
                                  * Enoxaparin 40 mg subcutaneously daily
                                  * Metoprolol succinate 100 mg orally daily
                                  Which drugs require dose reduction due to acute renal failure?

                                  A) All of her current medications
                                  B) Piperacillin/tazobactam, famotidine, and metoprolol succinate
                                  C) Piperacillin/tazobactam, famotidine, and enoxaparin
                                  D) Piperacillin/tazobactam, azithromycin, and enoxaparin


                                  Solutions:

                                  Question # 1
                                  Answer: A
                                  Question # 2
                                  Answer: A
                                  Question # 3
                                  Answer: C
                                  Question # 4
                                  Answer: D
                                  Question # 5
                                  Answer: C

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